Building a Biological Programming Structure


Engineering Intelligent Biological Systems


Developing Next-Generation Biological Security & Bio-Cryptography Tools


Developing Design Rules for Allosteric Networks


Next-generation Biosynthesis & Biomanufacturing


Growing Convergence Research: Biological, Electrical, & Chemical Engineering

The Wilson Research Laboratory at Georgia Institute of Technology - School of Chemical and Biomolecular Engineering, seeks to engineer novel, non-natural biological systems of bespoke function for high impact applications — while advancing our fundamental knowledge of protein and genetic structure-function relationships. The Wilson lab leverages a unique blend of iterative protein engineering and genetic engineering to design novel synthetic biological systems (i.e., biomolecular systems engineering). Our current focus is in the area of engineering cooperative systems of functional proteins and cognate genetic elements. To accomplish our goals, we employ workflows that involve rational protein design, synthetic biology, computational modeling, and laboratory evolution. These studies represent the most rigorous test of our understanding of structure-function and phylogenetic relationships; in addition to, promoting the development of novel biological tools that will benefit society.


Corey J. Wilson is an associate professor of Chemical and Biomolecular Engineering at the Georgia Institute of Technology. Prior to coming to Georgia Tech, he was an associate professor at Yale University in the Department of Chemical Engineering with a complimentary appointment in the Department of Biochemistry and Biophysics. The overarching theme of the Wilson Lab’s research is biomolecular engineering, with an emphasis on protein engineering. This effort involves a unique blend of iterative experimentation, computational protein design, and modeling. Current interests focus on designing novel energy transduction systems, designing enzymes for conditional catalysis, and the development of higher-order biosensing proteins that regulate gene expression.


2021Prof. Wilson Elected - American Institute for Medical and Biological Engineering (AIMBE): citation “For his seminal work in developing the field of Biomolecular Systems Engineering, Intelligent Microorganisms, and promoting diversity in STEM.”

2021Prof. Wilson Appointed - King-Chávez-Parks Professor.

2021Prof. Wilson Elected - National Society of Black Engineers (NSBE) Faculty Advisor at Georgia Tech.

2021The Wilson Lab Awarded a new NSF Grant to Engineer Intelligent Chassis Cells.

2021Congrats Thomas Groseclose! New Publication: Biomolecular Systems Engineering: Unlocking the Potential of Engineered Allostery via the Lactose Repressor Topology.

2021Congrats Ronald Rondon! New Publication: Engineering Alternate Ligand Recognition in the PurR Topology: A System of Novel Caffeine Biosensing Transcriptional Antirepressors.

2021Congrats Thomas Groseclose! REB Foundation Fellowship.

2021Congrats Andrew Short! Jewell Family Fellowship.

2021Congrats Zachary Herde! Award: Shell Outstanding GTA.

2021Congrats Brian D. Huang! NSF GRFP Honorable Mention.