Engineering Advanced Logical Operations for Gene Control


Examining the Origins of Engineered Allosteric Networks


Engineering Intelligent Microbes

The Wilson Research Laboratory at Georgia Institute of Technology - School of Chemical and Biomolecular Engineering, seeks to engineer novel, non-natural biological systems of bespoke function for high impact applications — while advancing our fundamental knowledge of protein and genetic structure-function relationships. The Wilson lab leverages a unique blend of iterative protein engineering and genetic engineering to design novel synthetic biological systems (i.e., biomolecular systems engineering). Our current focus is in the area of engineering cooperative systems of functional proteins and cognate genetic elements. To accomplish our goals, we employ workflows that involve rational protein design, synthetic biology, computational modeling, and laboratory evolution. These studies represent the most rigorous test of our understanding of structure-function and phylogenetic relationships; in addition to, promoting the development of novel biological tools that will benefit society.


Corey J. Wilson is an associate professor of Chemical and Biomolecular Engineering at the Georgia Institute of Technology. Prior to coming to Georgia Tech, he was an associate professor at Yale University in the Department of Chemical Engineering with a complimentary appointment in the Department of Biochemistry and Biophysics. The overarching theme of the Wilson Lab’s research is biomolecular engineering, with an emphasis on protein engineering. This effort involves a unique blend of iterative experimentation, computational protein design, and modeling. Current interests focus on designing novel energy transduction systems, designing enzymes for conditional catalysis, and the development of higher-order biosensing proteins that regulate gene expression.


2019Congrats Ronald Rondon! New Publication: Engineering a New Class of Anti-LacI Transcription Factors with Alternate DNA Recognition and ACS Synth Bio Editor's Choice Award.

2019Zachary Herde: Shell Outstanding Teaching Assistant and Thank a Teacher Recipient - ChBE 3130 Thermodynamics II.

2019Professor Corey J. Wilson Receives: “Thanks for Being a Great Teacher” Award – Thank a Teacher Certificate – ChBE 3130, Thermodynamics II: Georgia Institute of Technology.

2019 Professor Corey J. Wilson (Speaker): Rainin Foundation Innovations Symposium. An Emerging Transcriptional Programming Edifice - Introducing Biomolecular Systems Engineering.

2018 Welcome! Andrew Short (BioE Doctoral Graduate Student).

2018 The Wilson Lab Awarded a new NSF Grant to Engineer Differentiation.

2018 The Wilson Lab Awarded a new NSF Grant to Engineer Advanced Logical Operations for Gene Control.

2018 Professor Corey J. Wilson: Receives Faces of Inclusive Excellence Award.

2018 Congrats Tom! AiChE Outstanding Graduate Teaching Assistant Award and Eckert Graduate Development Award.

2018 Congrats Jamie! Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship Award.

2017 The Wilson Lab Awarded a new NSF Grant to Examine the Origins and Molecular Pathways of Alternate Allosteric Networks.