Engineering Advanced Logical Operations for Gene Control


Examining the Origins of Engineered Allosteric Networks


Engineering Intelligent Microbes

The Wilson Research Laboratory at Georgia Institute of Technology - School of Chemical and Biomolecular Engineering, seeks to engineer novel, non-natural biological systems of bespoke function for high impact applications — while advancing our fundamental knowledge of protein and genetic structure-function relationships. The Wilson lab leverages a unique blend of iterative protein engineering and genetic engineering to design novel synthetic biological systems (i.e., biomolecular systems engineering). Our current focus is in the area of engineering cooperative systems of functional proteins and cognate genetic elements. To accomplish our goals, we employ workflows that involve rational protein design, synthetic biology, computational modeling, and laboratory evolution. These studies represent the most rigorous test of our understanding of structure-function and phylogenetic relationships; in addition to, promoting the development of novel biological tools that will benefit society.


Corey J. Wilson is an associate professor of Chemical and Biomolecular Engineering at the Georgia Institute of Technology. Prior to coming to Georgia Tech, he was an associate professor at Yale University in the Department of Chemical Engineering with a complimentary appointment in the Department of Biochemistry and Biophysics. The overarching theme of the Wilson Lab’s research is biomolecular engineering, with an emphasis on protein engineering. This effort involves a unique blend of iterative experimentation, computational protein design, and modeling. Current interests focus on designing novel energy transduction systems, designing enzymes for conditional catalysis, and the development of higher-order biosensing proteins that regulate gene expression.


2020Congrats Thomas Groseclose! New Publication: Engineered systems of inducible anti-repressors for the next generation of biological programming.

2020Congrats James (Jamie) Davey! New Publication: Engineered signal-coupled inducible promoters: measuring the endogenous RNA-polymerase resource budget.

2020Congrats Zachary Herde! New Publication: Engineering Allosteric Communication.

2020Welcome! Milad Azimi (BioE Doctoral Graduate Student), Sumin Lee (ChBE Doctoral Graduate Student), and Ziqiao Zhang (EE Doctoral Graduate Student).

2020Congrats Zachary Herde! Arch McNeill ChBE Fellowship.

2020Professor Corey J. Wilson (Speaker): University of Florida, Department of Chemical Engineering.

2020 Professor Corey J. Wilson (Speaker): North Carolina State University, Department of Chemical and Biomolecular Engineering.

2019 The Wilson Lab Awarded a new GCR Grant - Biomolecular Systems Engineering - Unlocking the Potential of Biological Programming.

2019Professor Corey J. Wilson Receives: “Thanks for Being a Great Teacher” Award – Thank a Teacher Certificate – ChBE 3130, Thermodynamics II: Georgia Institute of Technology.